What is the significance of the Common Rule?

The Common Rule is significant because it provides a foundational framework of federal regulations that are aimed at protecting human subjects involved in research. This regulatory set of standards applies to studies conducted or funded by federal agencies, ensuring that the rights, welfare, and dignity of participants are safeguarded throughout the research process. It mandates key ethical principles, including informed consent, review by an Institutional Review Board (IRB), and the requirement to minimize risks to participants. The importance of the Common Rule lies in its role in promoting ethical research practices and maintaining public trust in the research community by ensuring that human participants are treated ethically and that their rights are protected.